Exosomes and other cell products

PURIFIED HUMAN ADIPOSE TISSUE DERIVED MESENCHYMAL STEM CELL EXOSOMES

Exosomes carry hundreds of growth factors, cytokines and micro ribonucleic acids (miRNAs) produced by the cultured stem cells. These bioactive molecules synergise to stimulate tissue regeneration and reduce inflammation. The regenerative substances found in exosomes include the following miRNA molecules: hsa-miR-144-3p, hsa-miR-199a-3p, hsa-miR-125b-3p, hsa-miR-29-3p, hsa-miR-100-5p, hsa-miR-424-5p, let-7a-5p, let-7b-5p. These molecules are rapidly decomposed in biologic fluids; however, membranes of the exosomes protect the bioactive cargo from degradation and ensures deep penetration into the tissue. Due to the high biocompatibility and low immunogenicity of the membranous envelope, exosomes can travel large distances and internalised by both neighbour and distant cells. Such a set of advantages makes exosomes good candidates for the development of regenerative cosmeceuticals and pharmaceuticals.

Free from bacterial contaminants. Sterile packaging in phosphate saline buffer, pH 7.4.

Packing:

• # 1-EP        100 μg of exosome protein
• # 1-EP        500 μg of exosome protein
• # 1-EP         5 mg of exosome protein
• # 1-EP         customized bulk

FOR RESEARCH USE ONLY. NOT FOR USE IN HUMAN THERAPEUTIC OR DIAGNOSTIC APPLICATIONS!