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WE INSTRUCT CELLS TO MAXIMISE EFFICIENCY OF THEIR NANOPARTICLES
Nanoparticles produced by cells can serve as novel medicines. Extracellular particles derived from healthy cells can restore sick cells to balance and cure diseases.
Exolitus scientists examine the therapeutic potential of each cell type contributing to the maintenance of the damaged tissue and select those producing nanoparticles with healing properties.
We then go one step extra and stimulate cells by signals that mimic the “HELP-ME” call from the diseased cells. As a result, the stimulated cells respond by producing healing nanoparticles.
Nanoparticles are concentrated, purified, lyophilised and stored without substantial bioactivity loss to be applied as medicines.
Exosomes are 30 – 130 nm membranous vesicles produced by cells and serving as cell-to cell delivery vehicles.
HOW WE MEASURE NANOPARTICLES
In the realm of nanotechnology, precision is paramount. To ensure our products deliver optimal results, we employ advanced measurement techniques that provide deep insights into the tiny particles at work. These methods not only guarantee the effectiveness of our formulations but also uphold the highest standards of safety and quality. Here’s a closer look at how we achieve this:
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Nanoparticle Tracking Analysis
Nanoparticle Tracking Analysis (NTA) is a powerful technique that allows to measure the size and concentration of particles. By shining a laser through the sample, NTA tracks the movement of individual particles. This precise measurement ensures that each formulation is optimized for the best results.
Products containing exosomes should have particles within 100-200nm range.
Cryo-microscopy
Cryo-Transmission Electron Microscopy (cryo-TEM) operates at extremely low temperatures (below -180°C) to preserve the natural state of nanoparticles. By keeping the samples in a vitrified (glass-like) state, cryo-TEM showcases the intricate structure of nanovesicles. This technique is particularly effective in highlighting the protective bilayer membrane, which shields the valuable cargo inside.
Why It Matters:
Quality Control: Ensures consistent particle size for better product performance.
Safety Compliance: Helps monitor and control nanoparticles to meet safety regulations.
Product Optimization: Provides data to refine formulations.
Contact Us
EXOLITUS, UAB
Kaunas, Lithuania Corp. ID 305464858
Kaunas, Lithuania Corp. ID 305464858
info@exolitus.com
Don’t hesitate to contact us
Don’t hesitate to contact us
+370 664 09669
We're ready to hear your requires
We're ready to hear your requires
Working Time
Mon-Fri: 9:00 - 17:00 / Closed on weekends
Mon-Fri: 9:00 - 17:00 / Closed on weekends